alpha 1 Fetoprotein Rabbit Polyclonal Antibody
Konjugasyon: Unconjugated
Rabbit polyclonal Antibody
Uygulama
Reaktivite
Human
Gen Adı
AFP
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | alpha 1 Fetoprotein Rabbit Polyclonal Antibody |
| Açıklama | Rabbit polyclonal Antibody |
| Konak | Rabbit |
| Reaktivite | Human |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Polyclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% sodium azide, pH 7.3. |
| Saflaştırma | Affinity Purification |
Antijen Bilgisi
| Gen Adı | AFP |
| Alternatif İsimler | Alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-fetoglobulin |
| Gen Kimliği | 174 |
| SwissProt Kimliği | P02771 |
| İmmünojen | The antiserum was produced against synthesized peptide derived from the Internal region of human AFP. AA range:371-420 |
Uygulama
| Uygulama | WB,IHC,ELISA |
| Seyreltme Oranı | WB 1:500-1:1000,IHC 1:50-1:100,ELISA 1:5000-1:20000 |
| Moleküler Ağırlık | Calculated MW: 69 kDa; Observed MW: 69 kDa |
Araştırma Alanı
| Cancer |
Arka Plan
| Alpha-fetoprotein (AFP) is a 65 kDa glycoprotein found in the mammalian fetal liver, yolk sac, and GI tract. In normal adult cells, p53 binds to the repressor region of the AFP gene, thereby blocking transcription. Mutations in both p53 and β-catenin are associated with aberrant expression of AFP. Research studies have shown that elevated serum AFP levels are predictive of hepatocellular carcinoma . |
