ZIP2 Rabbit Polyclonal Antibody
Konjugasyon: Unconjugated
Rabbit polyclonal Antibody
Uygulama
Reaktivite
Human,Rat,Mouse
Gen Adı
SLC39A2
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | ZIP2 Rabbit Polyclonal Antibody |
| Açıklama | Rabbit polyclonal Antibody |
| Konak | Rabbit |
| Reaktivite | Human,Rat,Mouse |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Polyclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% New type preservative N. |
| Saflaştırma | Affinity purification |
Antijen Bilgisi
| Gen Adı | SLC39A2 |
| Alternatif İsimler | SLC39A2; ZIP2; Zinc transporter ZIP2; 6A1; Eti-1; Solute carrier family 39 member 2; Zrt- and Irt-like protein 2; ZIP-2; hZIP2 |
| Gen Kimliği | 29986 |
| SwissProt Kimliği | Q9NP94 |
| İmmünojen | The antiserum was produced against synthesized peptide derived from human SLC39A2. AA range:11-60 |
Uygulama
| Uygulama | WB,ELISA |
| Seyreltme Oranı | WB 1:500-1:2000,ELISA 1:5000-1:20000 |
| Moleküler Ağırlık | 36kDa |
Araştırma Alanı
| Signal Transduction; Metabolism; Plasma Membrane; Channels; Types of disease; Cancer |
Arka Plan
| This gene encodes a member of the ZIP family of metal ion transporters. The encoded protein functions as a zinc transporter. Mutations in this gene may be associated with susceptibility to carotid artery disease. Multiple transcript variants have been described. [provided by RefSeq, Mar 2010],function:Mediates zinc uptake. Zinc uptake may be mediated by a Zn(2+)-HCO(3)(-) symport mechanism and can function in the presence of albumin. May also transport other divalent cations. May be important in contact inhibition of normal epithelial cells and loss of its expression may play a role in tumorigenesis.,induction:Shows a dramatic induction in normal epithelial cells contact inhibition.,miscellaneous:Zinc uptake is inhibited at pH levels below 7.0 and is stimulated at higher pH and is significantly inhibited by Cu(2+), Co(2+) and Mn(2+) ions. Not inhibited by Fe(2+).,similarity:Belongs to the ZIP transporter (TC 2.A.5) family.,tissue specificity:Expressed only in prostate and uterine epithelial cells., |
