Wnt5a Rabbit Monoclonal Antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
Human
Gen Adı
WNT5A
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | Wnt5a Rabbit Monoclonal Antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | Human |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein |
| Saflaştırma | Affinity Purification |
Antijen Bilgisi
| Gen Adı | WNT5A |
| Alternatif İsimler | WNT5A; Protein Wnt-5a |
| Gen Kimliği | 7474 |
| SwissProt Kimliği | P41221 |
| İmmünojen | A synthetic peptide of human Wnt5a |
Uygulama
| Uygulama | WB,ICC/IF |
| Seyreltme Oranı | WB 1:500-1:1000,ICC/IF 1:50-1:200 |
| Moleküler Ağırlık | Calculated MW: 42 kDa; Observed MW: 45 kDa |
Araştırma Alanı
| Neuroscience |
Arka Plan
| Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression. |
