Thrombomodulin Rabbit Monoclonal Antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
Mouse
Gen Adı
Thrombomodulin
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | Thrombomodulin Rabbit Monoclonal Antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | Mouse |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% protective protein. Stable for 12 months from date of receipt. |
| Saflaştırma | Affinity Purification |
Antijen Bilgisi
| Gen Adı | Thrombomodulin |
| Alternatif İsimler | TM; CD141; AI385582 |
| Gen Kimliği | 21824 |
| SwissProt Kimliği | P15306 |
| İmmünojen | Recombinant protein of mouse Thrombomodulin |
Uygulama
| Uygulama | WB,IHC,ICC/IF,FC,IP |
| Seyreltme Oranı | WB 1:500-1:2000,IHC 1:200-1:500,ICC/IF 1:100-1:200,FC 1:200-1:500,IP 1:20-1:50 |
| Moleküler Ağırlık | Calculated MW:62 kDa; Observed MW:105 kDa |
Araştırma Alanı
Arka Plan
| Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated. |
