TGF β1/3 Rabbit Monoclonal Antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
Human,Mouse,Rat
Gen Adı
TGFB1 TGFB3
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | TGF β1/3 Rabbit Monoclonal Antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | Human,Mouse,Rat |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG,Kappa |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%protective protein |
| Saflaştırma | Protein A |
Antijen Bilgisi
| Gen Adı | TGFB1 TGFB3 |
| Alternatif İsimler | Transforming growth factor beta-1 proprotein;Latency-associated peptide;LAP;Transforming growth factor beta-1;TGF-beta-1;Transforming growth factor beta-3 proprotein;Transforming growth factor beta-3;TGF-beta-3; |
| Gen Kimliği | 7040;7043 |
| SwissProt Kimliği | P01137;P10600 |
| İmmünojen | - |
Uygulama
| Uygulama | WB,ICC/IF,ELISA,IP |
| Seyreltme Oranı | WB 1:500-1:2000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200 |
| Moleküler Ağırlık | Calculated MW:44kD;Observed MW:44kD,13kD |
Araştırma Alanı
Arka Plan
| Cell localization:Secreted.This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic |
