S100A9 Rabbit Monoclonal Antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
Mouse,Rat
Gen Adı
S100A9
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | S100A9 Rabbit Monoclonal Antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | Mouse,Rat |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% protective protein. Stable for 12 months from date of receipt. |
| Saflaştırma | Affinity Purification |
Antijen Bilgisi
| Gen Adı | S100A9 |
| Alternatif İsimler | p14; Cagb; GAGB; L1Ag; BEE22; MRP14; 60B8Ag; AW546964 |
| Gen Kimliği | 20202 |
| SwissProt Kimliği | P31725 |
| İmmünojen | Recombinant protein of mouse S100A9 |
Uygulama
| Uygulama | WB,IHC,ICC/IF,FC |
| Seyreltme Oranı | WB 1:500-1:2000,IHC 1:200-1:500,ICC/IF 1:500-1:1000,FC 1:200-1:500 |
| Moleküler Ağırlık | Calculated MW:13 kDa; Observed MW:13 kDa |
Araştırma Alanı
Arka Plan
| S100A9 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis, adhesion, can increase the bactericidal activity of neutrophils by promoting phagocytosis via activation of SYK, PI3K/AKT, and ERK1/2 and can induce degranulation of neutrophils by a MAPK-dependent mechanism. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. |
