Relaxin Receptor 2 Rabbit Polyclonal Antibody
Konjugasyon: Unconjugated
Rabbit polyclonal Antibody
Uygulama
Reaktivite
Human,Mouse,Rat
Gen Adı
RXFP2
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | Relaxin Receptor 2 Rabbit Polyclonal Antibody |
| Açıklama | Rabbit polyclonal Antibody |
| Konak | Rabbit |
| Reaktivite | Human,Mouse,Rat |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Polyclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% New type preservative N. |
| Saflaştırma | Affinity purification |
Antijen Bilgisi
| Gen Adı | RXFP2 |
| Alternatif İsimler | RXFP2; GPR106; GREAT; LGR8; Relaxin receptor 2; G-protein coupled receptor 106; G-protein coupled receptor affecting testicular descent; Leucine-rich repeat-containing G-protein coupled receptor 8; Relaxin family peptide receptor 2 |
| Gen Kimliği | 122042 |
| SwissProt Kimliği | Q8WXD0 |
| İmmünojen | The antiserum was produced against synthesized peptide derived from human RXFP2. AA range:113-162 |
Uygulama
| Uygulama | WB,IHC |
| Seyreltme Oranı | WB 1:500-1:2000,IHC 1:50-1:300 |
| Moleküler Ağırlık | 86kDa |
Araştırma Alanı
| Neuroactive ligand-receptor interaction; |
Arka Plan
| This gene encodes a member of the GPCR (G protein-coupled, 7-transmembrane receptor) family. Mutations in this gene are associated with cryptorchidism. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009],caution:It is uncertain whether Met-1 or Met-18 is the initiator.,disease:Defects in RXFP2 are a cause of cryptorchidism [MIM:219050]; also known as impaired testicular descent. It is one of the most frequent congenital abnormalities in humans, involving 2-5% of male births. Cryptorchidism is associated with increased risk of infertility and testicular cancer.,function:Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3).,similarity:Belongs to the G-protein coupled receptor 1 family.,similarity:Contains 1 LDL-receptor class A domain.,similarity:Contains 10 LRR (leucine-rich) repeats.,tissue specificity:Expressed mainly in the brain, kidney, muscle, testis, thyroid, uterus, peripheral blood cells and bone marrow., |
