PCAF Rabbit Polyclonal Antibody
Konjugasyon: Unconjugated
Rabbit polyclonal Antibody
Uygulama
Reaktivite
Human,Mouse,Rat
Gen Adı
KAT2B
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | PCAF Rabbit Polyclonal Antibody |
| Açıklama | Rabbit polyclonal Antibody |
| Konak | Rabbit |
| Reaktivite | Human,Mouse,Rat |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Polyclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% New type preservative N. |
| Saflaştırma | Affinity purification |
Antijen Bilgisi
| Gen Adı | KAT2B |
| Alternatif İsimler | KAT2B; PCAF; Histone acetyltransferase KAT2B; Histone acetyltransferase PCAF; Histone acetylase PCAF; Lysine acetyltransferase 2B; P300/CBP-associated factor; P/CAF |
| Gen Kimliği | 8850 |
| SwissProt Kimliği | Q92831 |
| İmmünojen | The antiserum was produced against synthesized peptide derived from human p300/CBP. AA range:783-832 |
Uygulama
| Uygulama | WB,IHC,ICC/IF,ELISA |
| Seyreltme Oranı | WB 1:500-1:2000,IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:5000-1:20000 |
| Moleküler Ağırlık | 93kDa |
Araştırma Alanı
| Protein_Acetylation |
Arka Plan
| CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation. [provided by RefSeq, Jul 2008],chromatin organization,chromatin remodeling,transcription,regulation of transcription, DNA-dependent,protein amino acid acetylation,N-terminal protein amino acid acetylation,cell cycle,cell cycle arrest,negative regulation of cell proliferation,response to endogenous stimulus,response to hormone stimulus,response to organic substance,chromatin modification,covalent chromatin modification,histone modification,histone acetylation,N-terminal peptidyl-lysine acetylation,peptidyl-lysine modification,peptidyl-lysine acetylation,cell cycle process,N-terminal protein amino acid modification,response to insulin stimulus,cellular response to insulin stimulus,cellular response to hormone stimulus,regulation of cell proliferation,response to peptide hormone stimulus,protein amino acid acylation,regulation of transcription,regulation of RNA metabolic process,chromosome organization, |
