NDUFA1 Rabbit Monoclonal Antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
Human
Gen Adı
NDUFA1
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | NDUFA1 Rabbit Monoclonal Antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | Human |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG,Kappa |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%protective protein |
| Saflaştırma | Protein A |
Antijen Bilgisi
| Gen Adı | NDUFA1 |
| Alternatif İsimler | NDUFA1;NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 ;Complex I-MWFE;CI-MWFE;NADH-ubiquinone oxidoreductase MWFE subunit; |
| Gen Kimliği | 4694 |
| SwissProt Kimliği | O15239 |
| İmmünojen | A synthetic peptide of human NDUFA1 |
Uygulama
| Uygulama | WB,IHC,IP |
| Seyreltme Oranı | WB 1:1000-1:5000,IHC 1:100-1:300,IP 1:50-1:100 |
| Moleküler Ağırlık | Calculated MW:;Observed MW:8kD |
Araştırma Alanı
Arka Plan
| Cell localization:Mitochondrion inner membrane; Single-pass membrane protein; Matrix side..The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the "hydrophobic protein" (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function. [provided by RefSeq, Jul 2008], |
