Mre11 Rabbit Monoclonal antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
Human,Mouse,Rat
Gen Adı
MRE11
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | Mre11 Rabbit Monoclonal antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | Human,Mouse,Rat |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Monoclonal Antibody |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein |
| Saflaştırma | Affinity Purified |
Antijen Bilgisi
| Gen Adı | MRE11 |
| Alternatif İsimler | MRE11 homolog 1; Meiotic recombination 11 homolog A; MRE11 homolog A; MRE11A; HNGS1; MRE11 |
| Gen Kimliği | 4361 |
| SwissProt Kimliği | P49959 |
| İmmünojen | Recombinant protein of human Mre11 |
Uygulama
| Uygulama | WB,IHC |
| Seyreltme Oranı | WB 1:500-1:1000,IHC 1:50-1:100 |
| Moleküler Ağırlık | Calculated MW: 81 kDa; Observed MW: 81 kDa |
Araştırma Alanı
| Epigenetics and Nuclear Signaling |
Arka Plan
| DNA double-strand breaks are generated by ionizing radiation and endogenously produced radicals, and they often are repaired through the RAD52 homologous recombination pathway. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. |
