MMP8 (4B14) Rabbit Monoclonal Antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
Human,Mouse,Rat
Gen Adı
MMP8
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | MMP8 (4B14) Rabbit Monoclonal Antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | Human,Mouse,Rat |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Saflaştırma | Affinity purification |
Antijen Bilgisi
| Gen Adı | MMP8 |
| Alternatif İsimler | HNC; CLG1; MMP-8; PMNL-CL; COLLAGENASE I; NEUTROPHIL; matrix metalloproteinase 8; |
| Gen Kimliği | 4317 |
| SwissProt Kimliği | P22894 |
| İmmünojen | A synthetic peptide of human MMP8 |
Uygulama
| Uygulama | WB,IHC,IP,IF-P |
| Seyreltme Oranı | WB 1:1000-1:5000,IHC 1:100-1:200,IP 1:50-1:100,IF-P 1:100-1:200 |
| Moleküler Ağırlık | 53kDa |
Araştırma Alanı
| Angiogenesis |
Arka Plan
| Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Can degrade fibrillar type I, II, and III collagens. |
