MLK3 Rabbit Monoclonal antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
Human
Gen Adı
MAP3K11
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | MLK3 Rabbit Monoclonal antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | Human |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Monoclonal Antibody |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein |
| Saflaştırma | Affinity Purified |
Antijen Bilgisi
| Gen Adı | MAP3K11 |
| Alternatif İsimler | MAP3K11; MLK3; PTK1; SPRK; Mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; Src-homology 3 domain-containing proline-rich kinase |
| Gen Kimliği | 4296 |
| SwissProt Kimliği | Q16584 |
| İmmünojen | A synthetic peptide of human MLK3 |
Uygulama
| Uygulama | WB,ICC/IF |
| Seyreltme Oranı | WB 1:500-1:1000,ICC/IF 1:50-1:200 |
| Moleküler Ağırlık | Calculated MW: 93 kDa; Observed MW: 93 kDa |
Araştırma Alanı
| Signal Transduction |
Arka Plan
| The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. |
