IL-12A Rabbit Monoclonal Antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
Human, Mouse
Gen Adı
IL12A
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | IL-12A Rabbit Monoclonal Antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | Human, Mouse |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% protective protein. |
| Saflaştırma | Affinity Purification |
Antijen Bilgisi
| Gen Adı | IL12A |
| Alternatif İsimler | IL12A;Interleukin-12 subunit alpha, IL-12 subunit p35, IL-12A, Cytotoxic Lymphocyte Maturation Factor 35 kDa;NK cell stimulatory factor chain 1 ;NKSF1; |
| Gen Kimliği | 3592 |
| SwissProt Kimliği | P29459 |
| İmmünojen | A synthetic peptide of human IL12A |
Uygulama
| Uygulama | WB,IHC,FC |
| Seyreltme Oranı | WB 1:500-1:1000,IHC 1:50-1:100,FC 1:50-1:100 |
| Moleküler Ağırlık | Calculated MW:25 kDa;Observed MW: 35 kDa |
Araştırma Alanı
| Immunology |
Arka Plan
| Heterodimerizes with IL12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine .IL-12 is primarily produced by professional antigen-presenting cells (APCs) such as B-cells and dendritic cells (DCs) as well as macrophages and granulocytes and regulates T-cell and natural killer-cell responses, induces the production of interferon-gamma (IFN-gamma), favors the differentiation of T-helper 1 (Th1) cells and is an important link between innate resistance and adaptive immunity . |
