GCN5 Rabbit Polyclonal Antibody
Konjugasyon: Unconjugated
Rabbit polyclonal Antibody
Uygulama
Reaktivite
Human,Mouse
Gen Adı
KAT2A
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | GCN5 Rabbit Polyclonal Antibody |
| Açıklama | Rabbit polyclonal Antibody |
| Konak | Rabbit |
| Reaktivite | Human,Mouse |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Polyclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% New type preservative N. |
| Saflaştırma | Affinity purification |
Antijen Bilgisi
| Gen Adı | KAT2A |
| Alternatif İsimler | KAT2A; GCN5; GCN5L2; HGCN5; Histone acetyltransferase KAT2A; General control of amino acid synthesis protein 5-like 2; Histone acetyltransferase GCN5; HsGCN5; Lysine acetyltransferase 2A; STAF97 |
| Gen Kimliği | 2648 |
| SwissProt Kimliği | Q92830 |
| İmmünojen | The antiserum was produced against synthesized peptide derived from human GCN5L2. AA range:691-740 |
Uygulama
| Uygulama | WB,IHC,ICC/IF,ELISA |
| Seyreltme Oranı | WB 1:500-1:2000,IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:10000-1:20000 |
| Moleküler Ağırlık | 100kDa |
Araştırma Alanı
| Protein_Acetylation |
Arka Plan
| KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM, Sep 2009],somitogenesis,regionalization,chromatin organization,chromatin remodeling,transcription,transcription, DNA-dependent,regulation of transcription, DNA-dependent,regulation of transcription from RNA polymerase II promoter,transcription from RNA polymerase II promoter,protein amino acid acetylation,pattern specification process,embryonic development ending in birth or egg hatching,anterior/posterior pattern formation,chromatin modification,covalent chromatin modification,histone modification,histone acetylation,histone deubiquitination,protein deubiquitination,RNA biosynthetic process,segmentation,chordate embryonic development,protein amino acid acylation,histone H3 acetylation,regulation of transcription,regulation of RNA metabolic process,chromosome organization,protein modification by small protein removal,protein modification by small protein conjugation or removal, |
