FADD Rabbit Polyclonal Antibody
Konjugasyon: Unconjugated
Rabbit polyclonal Antibody
Uygulama
Reaktivite
Mouse
Gen Adı
Fadd
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | FADD Rabbit Polyclonal Antibody |
| Açıklama | Rabbit polyclonal Antibody |
| Konak | Rabbit |
| Reaktivite | Mouse |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Polyclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Saflaştırma | Affinity Chromatography |
Antijen Bilgisi
| Gen Adı | Fadd |
| Alternatif İsimler | FADD protein; GIG3; Growth inhibiting gene 3 protein; Mediator of receptor induced toxicity; MORT1 |
| Gen Kimliği | 14082 |
| SwissProt Kimliği | Q61160 |
| İmmünojen | A synthetic peptide of mouse FADD |
Uygulama
| Uygulama | WB,IHC,FC |
| Seyreltme Oranı | WB 1:500-1:1000,IHC 1:50-1:100,FC 1:50-1:100 |
| Moleküler Ağırlık | Calculated MW: 23 kDa; Observed MW: 28 kDa |
Araştırma Alanı
| Cell Biology |
Arka Plan
| Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. |
