ERK2 Rabbit Monoclonal Antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
Human,Mouse,Rat
Gen Adı
ERK2
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | ERK2 Rabbit Monoclonal Antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | Human,Mouse,Rat |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Purified antibody in TBS with 0.05% sodium azide,0.05%protective protein and 50% glycerol. |
| Saflaştırma | Affinity Purification |
Antijen Bilgisi
| Gen Adı | ERK2 |
| Alternatif İsimler | ERK; p38; p40; p41; ERT1; MAPK2; PRKM1; P42MAPK; p41mapk; MAPK |
| Gen Kimliği | 5594 |
| SwissProt Kimliği | P28482 |
| İmmünojen | A synthetic peptide of human ERK2 |
Uygulama
| Uygulama | WB,IHC,ICC,IP |
| Seyreltme Oranı | WB 1:500-1:1000,IHC 1:50-1:100,ICC 1:50-1:200,IP 1:10-1:20 |
| Moleküler Ağırlık | Calculated MW: 41 kDa; Observed MW: 41 kDa |
Araştırma Alanı
| Apoptosis,TGF-beta signaling pathway,PI3K-Akt signaling pathway,MAPK signaling pathway,Jak-STAT signaling pathway |
Arka Plan
| Act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of ERK2 requires its phosphorylation by upstream kinases. ERK2 is located in the cytoplasm of resting cells and translocates into the nucleus upon extracellular stimuli by active transport of a dimer. ERK2 is essential for placental development and ERK2 in the trophoblast compartment may be indispensable for the vascularization of the labyrinth. |
