Dnmt3a Rabbit Monoclonal antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
Human
Gen Adı
DNMT3A
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | Dnmt3a Rabbit Monoclonal antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | Human |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Monoclonal Antibody |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein |
| Saflaştırma | Affinity Purified |
Antijen Bilgisi
| Gen Adı | DNMT3A |
| Alternatif İsimler | DNMT3A2; M.HsaIIIA; Dnmt3a; MCMT; DNA methyltransferase 3a |
| Gen Kimliği | 1788 |
| SwissProt Kimliği | Q9Y6K1 |
| İmmünojen | A synthetic peptide of human Dnmt3a |
Uygulama
| Uygulama | WB |
| Seyreltme Oranı | WB 1:500-1:1000 |
| Moleküler Ağırlık | Calculated MW: 102 kDa; Observed MW: 130 kDa |
Araştırma Alanı
| Epigenetics and Nuclear Signaling |
Arka Plan
| Methylation of DNA at cytosine residues in mammalian cells is a heritable, epigenetic modification that is critical for proper regulation of gene expression, genomic imprinting and development. Three families of mammalian DNA methyltransferases have been identified: DNMT1, DNMT2 and DNMT3. DNMT1 is constitutively expressed in proliferating cells and functions as a maintenance methyltransferase, transferring proper methylation patterns to newly synthesized DNA during replication. |
