DUS2L Rabbit Polyclonal Antibody
Konjugasyon: Unconjugated
Rabbit polyclonal Antibody
Uygulama
Reaktivite
Human,Mouse
Gen Adı
DUS2L
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | DUS2L Rabbit Polyclonal Antibody |
| Açıklama | Rabbit polyclonal Antibody |
| Konak | Rabbit |
| Reaktivite | Human,Mouse |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Polyclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% New type preservative N. |
| Saflaştırma | Affinity purification |
Antijen Bilgisi
| Gen Adı | DUS2L |
| Alternatif İsimler | DUS2L; DUS2; tRNA-dihydrouridine(20) synthase [NAD(P)+]-like; Up-regulated in lung cancer protein 8; URLC8; tRNA-dihydrouridine synthase 2-like; hDUS2 |
| Gen Kimliği | 54920 |
| SwissProt Kimliği | Q9NX74 |
| İmmünojen | The antiserum was produced against synthesized peptide derived from human DUS2L. AA range:421-470 |
Uygulama
| Uygulama | WB,IHC,ICC/IF,ELISA |
| Seyreltme Oranı | WB 1:500-1:2000,IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:10000-1:20000 |
| Moleküler Ağırlık | 55kDa |
Araştırma Alanı
Arka Plan
| dihydrouridine synthase 2(DUS2) Homo sapiens This gene encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D-loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon-induced protein kinase. This gene has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012],cofactor:FAD.,function:Dihydrouridine synthase. Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.,similarity:Belongs to the dus family. Dus2 subfamily.,similarity:Contains 1 DRBM (double-stranded RNA-binding) domain.,subcellular location:Mainly at the endoplasmic reticulum.,subunit:Interacts with EPRS.,tissue specificity:Weak expression in heart, placenta and skeletal muscle. Up-regulated in most lung cancer cells (at protein level)., |
