Caspase 9 Rabbit Monoclonal antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
Mouse,Rat
Gen Adı
Casp9
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | Caspase 9 Rabbit Monoclonal antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | Mouse,Rat |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Monoclonal Antibody |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein |
| Saflaştırma | Affinity Purified |
Antijen Bilgisi
| Gen Adı | Casp9 |
| Alternatif İsimler | CASP 9; Caspase-9; CASP-9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; APAF-3; ICE-like apoptotic protease 6; ICE-LAP6; Caspase-9 subunit p35; Caspase-9 subunit p10; CASP9; MCH6 |
| Gen Kimliği | 12371 |
| SwissProt Kimliği | Q8C3Q9 |
| İmmünojen | Recombinant protein of mouse Caspase-9 |
Uygulama
| Uygulama | WB,IP |
| Seyreltme Oranı | WB 1:500-1:1000,IP 1:20-1:50 |
| Moleküler Ağırlık | Calculated MW: 50 kDa; Observed MW: 50 kDa |
Araştırma Alanı
| Cell Biology |
Arka Plan
| Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). |
