CRM1 Rabbit Monoclonal Antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
Human,Mouse,Rat
Gen Adı
CRM1
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | CRM1 Rabbit Monoclonal Antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | Human,Mouse,Rat |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Purified antibody in TBS with 0.05% sodium azide,0.05%protective protein and 50% glycerol. |
| Saflaştırma | Affinity Purification |
Antijen Bilgisi
| Gen Adı | CRM1 |
| Alternatif İsimler | XPO1; CRM1; Exportin-1; Exp1; Chromosome region maintenance 1 protein homolog |
| Gen Kimliği | 7514 |
| SwissProt Kimliği | O14980 |
| İmmünojen | A synthetic peptide of human CRM1 |
Uygulama
| Uygulama | WB,IHC,ICC |
| Seyreltme Oranı | WB 1:500-1:1000,IHC 1:50-1:100,ICC 1:50-1:200 |
| Moleküler Ağırlık | Calculated MW: 123 kDa; Observed MW: 123 kDa |
Araştırma Alanı
Arka Plan
| Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP). Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. |
