CNOT7 Rabbit Polyclonal Antibody
Konjugasyon: Unconjugated
Rabbit polyclonal Antibody
Uygulama
Reaktivite
Human,Mouse,Rat,Monkey
Gen Adı
Cnot7
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | CNOT7 Rabbit Polyclonal Antibody |
| Açıklama | Rabbit polyclonal Antibody |
| Konak | Rabbit |
| Reaktivite | Human,Mouse,Rat,Monkey |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Polyclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein |
| Saflaştırma | Affinity Purification |
Antijen Bilgisi
| Gen Adı | Cnot7 |
| Alternatif İsimler | CCR4-associated factor 1; CAF-1 |
| Gen Kimliği | 18983 |
| SwissProt Kimliği | Q60809 |
| İmmünojen | A synthetic peptide of mouse CNOT7 |
Uygulama
| Uygulama | WB,IHC,FC,IP |
| Seyreltme Oranı | WB 1:500-1:1000,IHC 1:50-1:100,FC 1:50-1:100,IP 1:20-1:50 |
| Moleküler Ağırlık | Calculated MW: 33 kDa; Observed MW: 33 kDa |
Araştırma Alanı
| Epigenetics and Nuclear Signaling |
Arka Plan
| Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. |
