CCDC98 Rabbit Monoclonal Antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
Human
Gen Adı
CCDC98
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | CCDC98 Rabbit Monoclonal Antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | Human |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Purified antibody in PBS with 0.05% sodium azide,0.05% protective protein and 50% glycerol. |
| Saflaştırma | Affinity Purification |
Antijen Bilgisi
| Gen Adı | CCDC98 |
| Alternatif İsimler | ABRA1; ABRAXAS; FAM175A;;ABRAXAS1 |
| Gen Kimliği | - |
| SwissProt Kimliği | Q6UWZ7 |
| İmmünojen | A synthesized peptide derived from human ABRAXAS1 |
Uygulama
| Uygulama | WB,ICC,FC,IP |
| Seyreltme Oranı | WB 1:1000-1:2000,ICC 1:50-1:200,FC 1:20-1:100,IP 1:20-1:50 |
| Moleküler Ağırlık | Calculated MW: 47 kDa ; Observed MW: 50 kDa |
Araştırma Alanı
Arka Plan
| Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. |