Bradykinin B1 R Rabbit Polyclonal Antibody
Konjugasyon: Unconjugated
Rabbit polyclonal Antibody
Uygulama
Reaktivite
Human,Rat,Mouse
Gen Adı
BDKRB1
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | Bradykinin B1 R Rabbit Polyclonal Antibody |
| Açıklama | Rabbit polyclonal Antibody |
| Konak | Rabbit |
| Reaktivite | Human,Rat,Mouse |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Polyclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% New type preservative N. |
| Saflaştırma | Affinity purification |
Antijen Bilgisi
| Gen Adı | BDKRB1 |
| Alternatif İsimler | BDKRB1; BRADYB1; B1 bradykinin receptor; B1R; BK-1 receptor |
| Gen Kimliği | 623 |
| SwissProt Kimliği | P46663 |
| İmmünojen | The antiserum was produced against synthesized peptide derived from human BDKRB1. AA range:201-250 |
Uygulama
| Uygulama | WB,ICC/IF,ELISA |
| Seyreltme Oranı | WB 1:500-1:2000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:10000 |
| Moleküler Ağırlık | 40kDa |
Araştırma Alanı
| Calcium;Neuroactive ligand-receptor interaction;Complement and coagulation cascades;Regulates Actin and Cytoskeleton; |
Arka Plan
| Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],function:This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.,online information:Bradykinin receptor entry,similarity:Belongs to the G-protein coupled receptor 1 family., |
