BAG2 (17W11) Rabbit Monoclonal Antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
Human,Mouse,Rat
Gen Adı
BAG2
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | BAG2 (17W11) Rabbit Monoclonal Antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | Human,Mouse,Rat |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Saflaştırma | Affinity purification |
Antijen Bilgisi
| Gen Adı | BAG2 |
| Alternatif İsimler | BAG 2; Bag2; |
| Gen Kimliği | 9532 |
| SwissProt Kimliği | O95816 |
| İmmünojen | A synthetic peptide of human BAG2 |
Uygulama
| Uygulama | WB,ICC/IF |
| Seyreltme Oranı | WB 1:500-1:2000,ICC/IF 1:100-1:200 |
| Moleküler Ağırlık | 24kDa |
Araştırma Alanı
| Cell Biology; Apoptosis; Intracellular; Bcl2 Family; Signal Transduction; Protein Trafficking; Chaperones; Cancer; Cell Death |
Arka Plan
| Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release (PubMed:24318877, PubMed:9873016). |
