BACE1 Rabbit Monoclonal Antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
Rat
Gen Adı
Bace1
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | BACE1 Rabbit Monoclonal Antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | Rat |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein |
| Saflaştırma | Affinity Purification |
Antijen Bilgisi
| Gen Adı | Bace1 |
| Alternatif İsimler | ASP2; Bace; C76936 |
| Gen Kimliği | 23821 |
| SwissProt Kimliği | P56818 |
| İmmünojen | Recombinant protein of mouse BACE1 |
Uygulama
| Uygulama | WB,IP |
| Seyreltme Oranı | WB 1:500-1:1000,IP 1:20-1:50 |
| Moleküler Ağırlık | Calculated MW: 56 kDa; Observed MW: 70 kDa |
Araştırma Alanı
| Neuroscience |
Arka Plan
| Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. Cleaves APP with much more catalytic efficiency than for the wild-type. |
