Axin 2 Rabbit Polyclonal Antibody
Konjugasyon: Unconjugated
Rabbit polyclonal Antibody
Uygulama
Reaktivite
Human,Mouse,Rat
Gen Adı
AXIN2
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | Axin 2 Rabbit Polyclonal Antibody |
| Açıklama | Rabbit polyclonal Antibody |
| Konak | Rabbit |
| Reaktivite | Human,Mouse,Rat |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Polyclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Saflaştırma | Affinity Chromatography |
Antijen Bilgisi
| Gen Adı | AXIN2 |
| Alternatif İsimler | Axil; Axin like protein; Axin2; Axis inhibition protein 2; Conductin |
| Gen Kimliği | 8313 |
| SwissProt Kimliği | Q9Y2T1 |
| İmmünojen | A synthetic peptide of human Axin 2 |
Uygulama
| Uygulama | WB,IHC,ICC/IF |
| Seyreltme Oranı | WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200 |
| Moleküler Ağırlık | Calculated MW: 94 kDa; Observed MW: 94 kDa |
Araştırma Alanı
| Cell Biology |
Arka Plan
| Axin1 (Axis inhibition protein 1) and Axin2 are multidomain scaffold proteins that negatively regulate Wnt signaling. Axin1 interacts with APC, GSK-3β, Dvl, and β-catenin and promotes the GSK-3β-mediated phosphorylation and subsequent degradation of β-catenin .Down-regulates beta-catenin. |
