AKAP 110 Rabbit Polyclonal Antibody
Konjugasyon: Unconjugated
Rabbit polyclonal Antibody
Uygulama
Reaktivite
Human,Mouse
Gen Adı
AKAP3
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | AKAP 110 Rabbit Polyclonal Antibody |
| Açıklama | Rabbit polyclonal Antibody |
| Konak | Rabbit |
| Reaktivite | Human,Mouse |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Polyclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% New type preservative N. |
| Saflaştırma | Affinity purification |
Antijen Bilgisi
| Gen Adı | AKAP3 |
| Alternatif İsimler | AKAP3; AKAP110; SOB1; A-kinase anchor protein 3; AKAP-3; A-kinase anchor protein 110 kDa; AKAP 110; Cancer/testis antigen 82; CT82; Fibrous sheath protein of 95 kDa; FSP95; Fibrousheathin I; Fibrousheathin-1; Protein kinase A-anchoring prot |
| Gen Kimliği | 10566 |
| SwissProt Kimliği | O75969 |
| İmmünojen | The antiserum was produced against synthesized peptide derived from human AKAP3. AA range:191-240 |
Uygulama
| Uygulama | ICC/IF,ELISA |
| Seyreltme Oranı | ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000 |
| Moleküler Ağırlık | - |
Araştırma Alanı
Arka Plan
| This gene encodes a member of A-kinase anchoring proteins (AKAPs), a family of functionally related proteins that target protein kinase A to discrete locations within the cell. The encoded protein is reported to participate in protein-protein interactions with the R-subunit of the protein kinase A as well as sperm-associated proteins. This protein is expressed in spermatozoa and localized to the acrosomal region of the sperm head as well as the length of the principal piece. It may function as a regulator of motility, capacitation, and the acrosome reaction. [provided by RefSeq, May 2013],domain:RII-binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer.,function:May function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction.,PTM:Phosphorylated on tyrosine residues.,similarity:Belongs to the AKAP110 family.,subcellular location:Ribs of the fibrous sheath in the principal piece of the sperm tail. Dorsal margin of the acrosomal segment.,subunit:Interacts with ROPN1 AND ROPN1L.,tissue specificity:Testis specific; only expressed in spermatids., |
