ADI1 Rabbit Polyclonal Antibody
Konjugasyon: Unconjugated
Rabbit polyclonal Antibody
Uygulama
Reaktivite
Human,Mouse,Rat
Gen Adı
ADI1
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | ADI1 Rabbit Polyclonal Antibody |
| Açıklama | Rabbit polyclonal Antibody |
| Konak | Rabbit |
| Reaktivite | Human,Mouse,Rat |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Polyclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% New type preservative N. |
| Saflaştırma | Affinity purification |
Antijen Bilgisi
| Gen Adı | ADI1 |
| Alternatif İsimler | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54;Acireductone dioxygenase (Fe(2+)-requiring);ARD;Fe-ARD;Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1;MTCBP-1;Submergence-induced protein-like factor;Sip-L) |
| Gen Kimliği | 55256 |
| SwissProt Kimliği | Q9BV57 |
| İmmünojen | The antiserum was produced against synthesized peptide derived from the Internal region of human ADI1. AA range:71-120 |
Uygulama
| Uygulama | IHC,ICC/IF,ELISA |
| Seyreltme Oranı | IHC 1:50-1:200,ICC/IF 1:50-1:200,ELISA 1:10000-1:20000 |
| Moleküler Ağırlık | - |
Araştırma Alanı
| Cysteine and methionine metabolism; |
Arka Plan
| This gene encodes an enzyme that belongs to the aci-reductone dioxygenase family of metal-binding enzymes, which are involved in methionine salvage. This enzyme may regulate mRNA processing in the nucleus, and may carry out different functions depending on its localization. Related pseudogenes have been defined on chromosomes 8 and 20. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015],cofactor:Binds 1 nickel ion per monomer. Can also use other divalent metal cations.,function:Has aci-reductone dioxygenase (ARD) activity and can function in the 5-methylthioadenosine (MTA) methionine salvage pathway. Down-regulates cell migration mediated by MMP14. Necessary for hepatitis C virus replication in an otherwise non-permissive cell line.,pathway:Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from (S)-methyl-5-thio-alpha-D-ribose 1-phosphate: step 5/6.,similarity:Belongs to the acireductone dioxygenase (ARD) family.,subunit:Interacts with MMP14.,tissue specificity:Detected in heart, colon, lung, stomach, brain, spleen, liver, skeletal muscle and kidney., |
