ACE1 (17Q3) Rabbit Monoclonal Antibody

ACE1 (17Q3) Rabbit Monoclonal Antibody

Summary

Production Name

ACE1 (17Q3) Rabbit Monoclonal Antibody

Description

Recombinant rabbit monoclonal antibody

Host

Rabbit

Application

WB,IHC,IF-P

Reactivity

Human,Mouse

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Purification

Affinity purification

 

Immunogen

Gene Name

ACE

Alternative Names

Angiotensin-converting enzyme; somatic isoform precursor; CD143 antigen; DCP; DCP1; Dipeptidyl carboxypeptidase I; Kininase II;

Gene ID

1636

SwissProt ID

P12821

 

Application

Dilution Ratio

WB 1:500-1:2000,IHC 1:100-1:200,IF-P 1:100-1:200

Molecular Weight

150kDa

 

Background

Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety. Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety.

 

Research Area

Cardiovascular; Blood; Serum Proteins; Stem Cells; Hematopoietic Progenitors; Surface Molecules; Signal Transduction; Metabolism; Vitamins / Minerals; Cell Biology; Proteolysis / Ubiquitin; Proteolytic enzymes; Metalloprotease; ACEs; Vasculature; Vasoconstriction; Cancer; Cancer Metabolism; Response to hypoxia; Kits/ Lysates/ Other; Kits; ELISA Kits; Cardiovascular ELISA kits; Metabolism; Pathways and Processes; Cofactors, Vitamins / minerals; Hypoxia

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