phospho-Eralpha(Tyr-537) Mouse Monoclonal Antibody
Konjugasyon: Unconjugated
Mouse monoclonal Antibody
Uygulama
Reaktivite
Human
Gen Adı
phospho-Eralpha(Tyr-537)
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | phospho-Eralpha(Tyr-537) Mouse Monoclonal Antibody |
| Açıklama | Mouse monoclonal Antibody |
| Konak | Mouse |
| Reaktivite | Human |
| Konjugasyon | Unconjugated |
| Modifikasyon | Phosphorylated |
| İzotip | Mouse IgG1 |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Purified antibody in PBS with 0.05% sodium azide |
| Saflaştırma | Affinity Purification |
Antijen Bilgisi
| Gen Adı | phospho-Eralpha(Tyr-537) |
| Alternatif İsimler | ESR1;ER; ESR; Era; ESRA; ESTRR; NR3A1 |
| Gen Kimliği | 2099 |
| SwissProt Kimliği | P03372 |
| İmmünojen | Synthesized peptide of human Eralpha(AA: 530-542 (Tyr-537)) expressed in E. Coli. |
Uygulama
| Uygulama | ELISA,FC |
| Seyreltme Oranı | ELISA 1:5000-1:20000,FC 1:200-1:400 |
| Moleküler Ağırlık | 66.2kDa |
Araştırma Alanı
Arka Plan
| This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. |
