XRN1 Mouse Monoclonal Antibody
Konjugasyon: Unconjugated
Mouse monoclonal Antibody
Uygulama
Reaktivite
Human, Mouse
Gen Adı
XRN1
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | XRN1 Mouse Monoclonal Antibody |
| Açıklama | Mouse monoclonal Antibody |
| Konak | Mouse |
| Reaktivite | Human, Mouse |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | Mouse IgG1 |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Purified antibody in PBS with 0.05% sodium azide. |
| Saflaştırma | Affinity Purification |
Antijen Bilgisi
| Gen Adı | XRN1 |
| Alternatif İsimler | 5'-3' exoribonuclease 1, 3.1.13.-, Strand-exchange protein 1 homolog, XRN1, SEP1 |
| Gen Kimliği | 54464 |
| SwissProt Kimliği | Q8IZH2 |
| İmmünojen | This XRN1 antibody is generated from a mouse immunized with arecombinant protein between1455-1706 amino acids from human XRN1. |
Uygulama
| Uygulama | WB |
| Seyreltme Oranı | WB 1:1000-1:2000 |
| Moleküler Ağırlık | 194.1kDa |
Araştırma Alanı
Arka Plan
| Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS). |
