ULBP1 (3U10) Rabbit Monoclonal Antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
Human
Gen Adı
ULBP1
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | ULBP1 (3U10) Rabbit Monoclonal Antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | Human |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Saflaştırma | Affinity purification |
Antijen Bilgisi
| Gen Adı | ULBP1 |
| Alternatif İsimler | Alcan beta; N2DL1; NKG2DL1; RAET1I; UL16; UL16 binding protein 1; ULBP1; |
| Gen Kimliği | 80329 |
| SwissProt Kimliği | Q9BZM6 |
| İmmünojen | Recombinant protein of human ULBP1 |
Uygulama
| Uygulama | FC |
| Seyreltme Oranı | FC 1:50-1:100 |
| Moleküler Ağırlık | 28kDa |
Araştırma Alanı
Arka Plan
| Ligand for the NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity. |
