Thrombomodulin/CD141 Rabbit Monoclonal Antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
Mouse,Rat
Gen Adı
Thrombomodulin/CD141
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | Thrombomodulin/CD141 Rabbit Monoclonal Antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | Mouse,Rat |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Purified antibody in PBS with 0.05% sodium azide,0.05% protective protein and 50% glycerol. |
| Saflaştırma | Affinity Purification |
Antijen Bilgisi
| Gen Adı | Thrombomodulin/CD141 |
| Alternatif İsimler | AHUS6; BDCA3; CD141; CD141 antigen; Fetomodulin; Thbd; THPH12; THRM; Thrombomodulin; ;Thrombomodulin |
| Gen Kimliği | - |
| SwissProt Kimliği | P15306(mouse)(human:P07204) |
| İmmünojen | A synthesized peptide derived from mouse Thrombomodulin |
Uygulama
| Uygulama | WB,IHC,FC |
| Seyreltme Oranı | WB 1:1000-1:2000,IHC 1:100-1:200,FC 1:20-1:100 |
| Moleküler Ağırlık | Calculated MW: 62 kDa ; Observed MW: 105,70 kDa |
Araştırma Alanı
Arka Plan
| Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated. |
