TRIM25 Mouse Monoclonal Antibody
Konjugasyon: Unconjugated
Mouse monoclonal Antibody
Uygulama
Reaktivite
Human
Gen Adı
TRIM25
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | TRIM25 Mouse Monoclonal Antibody |
| Açıklama | Mouse monoclonal Antibody |
| Konak | Mouse |
| Reaktivite | Human |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | Mouse IgG2b |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Purified antibody in PBS with 0.05% sodium azide |
| Saflaştırma | Affinity Purification |
Antijen Bilgisi
| Gen Adı | TRIM25 |
| Alternatif İsimler | EFP; Z147; RNF147; ZNF147 |
| Gen Kimliği | 7706 |
| SwissProt Kimliği | Q14258 |
| İmmünojen | Purified recombinant fragment of human TRIM25 (AA: 211-360) expressed in E. Coli. |
Uygulama
| Uygulama | WB,IHC,ICC,ELISA,FC |
| Seyreltme Oranı | WB 1:500-1:2000,IHC 1:200-1:1000,ICC 1:50-1:250,ELISA 1:5000-1:20000,FC 1:200-1:400 |
| Moleküler Ağırlık | 71kDa |
Araştırma Alanı
Arka Plan
| The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene. |
