SV40 T Antigen Rabbit Monoclonal Antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
All
Gen Adı
-
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | SV40 T Antigen Rabbit Monoclonal Antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | All |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein |
| Saflaştırma | Affinity Purification |
Antijen Bilgisi
| Gen Adı | - |
| Alternatif İsimler | Large T antigen; LT; LT-AG |
| Gen Kimliği | 29031019 |
| SwissProt Kimliği | P03070 |
| İmmünojen | Recombinant protein SV40 Large T Antigen |
Uygulama
| Uygulama | WB,ICC/IF,IP |
| Seyreltme Oranı | WB 1:500-1:1000,ICC/IF 1:50-1:200,IP 1:20-1:50 |
| Moleküler Ağırlık | Calculated MW: 82 kDa; Observed MW: 90 kDa |
Araştırma Alanı
| Infectious Diseases |
Arka Plan
| Isoform large T antigen is a key early protein essential for both driving viral replication and inducing cellular transformation. Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle and by autoregulating the synthesis of viral early mRNA. Displays highly oncogenic activities by corrupting the host cellular checkpoint mechanisms that guard cell division and the transcription, replication, and repair of DNA. |
