STAT4 Rabbit Monoclonal Antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
Human
Gen Adı
STAT4
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | STAT4 Rabbit Monoclonal Antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | Human |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Purified antibody in PBS with 0.05% sodium azide,0.05% protective protein and 50% glycerol. |
| Saflaştırma | Affinity Purification |
Antijen Bilgisi
| Gen Adı | STAT4 |
| Alternatif İsimler | Signal transducer and activator of transcription 4; Stat-4; Stat 4;;STAT4 |
| Gen Kimliği | - |
| SwissProt Kimliği | Q14765 |
| İmmünojen | A synthesized peptide derived from human STAT4 |
Uygulama
| Uygulama | WB,IHC,ICC/IF,ICC,FC,IP |
| Seyreltme Oranı | WB 1:1000-1:2000,IHC 1:100-1:200,ICC/IF 1:50-1:200,ICC 1:50-1:200,FC 1:20-1:100,IP 1:20-1:50 |
| Moleküler Ağırlık | 86 kDa |
Araştırma Alanı
Arka Plan
| Transcriptional regulator mainly expressed in hematopoietic cells that plays a critical role in cellular growth, differentiation and immune response .Plays a key role in the differentiation of T-helper 1 cells and the production of interferon-gamma.Participates also in multiple neutrophil functions including chemotaxis and production of the neutrophil extracellular traps (By similarity).After IL12 binding to its receptor IL12RB2, STAT4 interacts with the intracellular domain of IL12RB2 and becomes tyrosine phosphorylated. |