SMAD1 Mouse Monoclonal Antibody
Konjugasyon: Unconjugated
Mouse monoclonal Antibody
Uygulama
Reaktivite
Human
Gen Adı
SMAD1
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | SMAD1 Mouse Monoclonal Antibody |
| Açıklama | Mouse monoclonal Antibody |
| Konak | Mouse |
| Reaktivite | Human |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | Mouse IgG1 |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Purified antibody in PBS with 0.05% sodium azide. |
| Saflaştırma | Affinity Purification |
Antijen Bilgisi
| Gen Adı | SMAD1 |
| Alternatif İsimler | Mothers against decapentaplegic homolog 1, MAD homolog 1, Mothers against DPP homolog 1, JV4-1, Mad-related protein 1, SMAD family member 1, SMAD 1, Smad1, hSMAD1, Transforming growth factor-beta-signaling protein 1, BSP-1, SMAD1, BSP1, MADH1, MADR1 |
| Gen Kimliği | 4086 |
| SwissProt Kimliği | Q15797 |
| İmmünojen | This SMAD1 antibody is generated from a mouse immunized with a recombinant protein between 20-330 amino acids from human SMAD1. |
Uygulama
| Uygulama | WB,IHC,FC |
| Seyreltme Oranı | WB 1:1000-1:2000,IHC 1:100-1:500,FC 1:25-1:50 |
| Moleküler Ağırlık | 52.3kDa |
Araştırma Alanı
| TGF-beta signaling pathway |
Arka Plan
| Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. |
