S100 alpha 6 (12M1) Rabbit Monoclonal Antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
Human
Gen Adı
S100A6
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | S100 alpha 6 (12M1) Rabbit Monoclonal Antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | Human |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Saflaştırma | Affinity purification |
Antijen Bilgisi
| Gen Adı | S100A6 |
| Alternatif İsimler | Protein S100-A6; Calcyclin; MLN 4; PRA; CACY; CABP; 5B10; |
| Gen Kimliği | 6277 |
| SwissProt Kimliği | P06703 |
| İmmünojen | Recombinant protein of human S100 alpha 6/PRA |
Uygulama
| Uygulama | WB,IHC,ICC/IF |
| Seyreltme Oranı | WB 1:500-1:2000,IHC 1:50-1:100,ICC/IF 1:200-1:500 |
| Moleküler Ağırlık | 10kDa |
Araştırma Alanı
| Cell Biology |
Arka Plan
| S100A6 (calcyclin) is involved in a number of cellular processes, including exocytosis and cell cycle regulation. In addition, S100A6 interacts with a number of proteins such as SIP, GAPDH, and annexins in a calcium-dependent fashion. Research studies demonstrate that a down regulation of corresponding S100A6 gene expression causes a decrease in cell proliferation. May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative. |
