RET Mouse Monoclonal Antibody
Konjugasyon: Unconjugated
Mouse monoclonal Antibody
Uygulama
Reaktivite
Human
Gen Adı
RET
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | RET Mouse Monoclonal Antibody |
| Açıklama | Mouse monoclonal Antibody |
| Konak | Mouse |
| Reaktivite | Human |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | Mouse IgM |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Purified antibody in PBS with 0.05% sodium azide. |
| Saflaştırma | Affinity Purification |
Antijen Bilgisi
| Gen Adı | RET |
| Alternatif İsimler | Proto-oncogene tyrosine-protein kinase receptor Ret, Cadherin family member 12, Proto-oncogene c-Ret, Soluble RET kinase fragment, Extracellular cell-membrane anchored RET cadherin 120 kDa fragment, RET, CDHF12, CDHR16, PTC, RET51 |
| Gen Kimliği | 5979 |
| SwissProt Kimliği | P07949 |
| İmmünojen | This RET Monoclonal antibody was raised using purified His-tagged recombinant human RET. |
Uygulama
| Uygulama | WB,IHC,ICC |
| Seyreltme Oranı | WB 1:500-1:2000,IHC 1:100-1:500,ICC 1:20-1:50 |
| Moleküler Ağırlık | 124.3kDa |
Araştırma Alanı
Arka Plan
| This gene, a member of the cadherin superfamily, encodesone of the receptor tyrosine kinases, which are cell-surfacemolecules that transduce signals for cell growth anddifferentiation. This gene plays a crucial role in neural crestdevelopment, and it can undergo oncogenic activation in vivo and invitro by cytogenetic rearrangement. Mutations in this gene areassociated with the disorders multiple endocrine neoplasia, typeIIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease,and medullary thyroid carcinoma. Two transcript variants encodingdifferent isoforms have been found for this gene. Additionaltranscript variants have been described but their biologicalvalidity has not been confirmed. |
