RAPGEF5 Rabbit Monoclonal Antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
Human,Mouse,Rat
Gen Adı
RAPGEF5
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | RAPGEF5 Rabbit Monoclonal Antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | Human,Mouse,Rat |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% protective protein. Stable for 12 months from date of receipt. |
| Saflaştırma | Affinity Purification |
Antijen Bilgisi
| Gen Adı | RAPGEF5 |
| Alternatif İsimler | GFR; REPAC; MR-GEF |
| Gen Kimliği | 9771, 217944, 362799 |
| SwissProt Kimliği | Q92565, Q8C0Q9, P83900 |
| İmmünojen | A synthetic peptide of human RAPGEF5 |
Uygulama
| Uygulama | WB,IHC,ICC/IF,FC |
| Seyreltme Oranı | WB 1:1000-1:5000,IHC 1:200-1:500,ICC/IF 1:100-1:200,FC 1:10-1:100 |
| Moleküler Ağırlık | Calculated MW:68 kDa; Observed MW:68-75 kDa |
Araştırma Alanı
Arka Plan
| Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008] |
