RAIDD Rabbit Monoclonal antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
Human
Gen Adı
CRADD
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | RAIDD Rabbit Monoclonal antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | Human |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Monoclonal Antibody |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein |
| Saflaştırma | Affinity Purified |
Antijen Bilgisi
| Gen Adı | CRADD |
| Alternatif İsimler | CRADD; MGC9163; RAIDD; Death adaptor molecule RAIDD; Death domain containing protein CRADD |
| Gen Kimliği | 8738 |
| SwissProt Kimliği | P78560 |
| İmmünojen | A synthetic peptide of human RAIDD |
Uygulama
| Uygulama | WB,ICC/IF,IP |
| Seyreltme Oranı | WB 1:500-1:1000,ICC/IF 1:50-1:200,IP 1:20-1:50 |
| Moleküler Ağırlık | Calculated MW: 23 kDa; Observed MW: 23 kDa |
Araştırma Alanı
| Cell Biology |
Arka Plan
| The receptor interacting protein RIP is a death domain-containing serine/threonine kinase which associates with FAS or the TNF-R1 binding protein TRADD. RAIDD (RIP-associated ICH-1/Ced-3 homologous protein with a death domain) has been identified as a RIP binding protein that also associates with members of the caspase family, providing a link between activation of the TNF-Rs and the triggering of the cysteine protease cascade. The amino-terminal domain of RAIDD shares significant homology with the prodomain of ICH-1 and mediates the binding of RAIDD to this cysteine protease. |
