Phospho-MLKL(S345) Rabbit Monoclonal Antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
Mouse
Gen Adı
Phospho-MLKL(S345)
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | Phospho-MLKL(S345) Rabbit Monoclonal Antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | Mouse |
| Konjugasyon | Unconjugated |
| Modifikasyon | Phosphorylated |
| İzotip | IgG |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Purified antibody in PBS with 0.05% sodium azide,0.05% protective protein and 50% glycerol. |
| Saflaştırma | Affinity Purification |
Antijen Bilgisi
| Gen Adı | Phospho-MLKL(S345) |
| Alternatif İsimler | hMLKL ; Mixed lineage kinase domain like; Mixed lineage kinase domain like protein; Mixed lineage kinase domain like pseudokinase;;p-Mlkl (S345) |
| Gen Kimliği | - |
| SwissProt Kimliği | Q9D2Y4(mouse)Q8NB16(Human) |
| İmmünojen | A synthesized peptide derived from mouse Mlkl around the phosphorylation site of S345 |
Uygulama
| Uygulama | WB,IP |
| Seyreltme Oranı | WB 1:1000-1:2000,IP 1:20-1:50 |
| Moleküler Ağırlık | 54 kDa |
Araştırma Alanı
Arka Plan
| Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process.Does not have protein kinase activity.Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. |
