Phospho-Histone H2A.X (Ser139) Mouse Monoclonal Antibody
Konjugasyon: Unconjugated
Mouse monoclonal Antibody
Uygulama
Reaktivite
Human,Mouse
Gen Adı
Phospho-Histone H2A.X (Ser139)
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | Phospho-Histone H2A.X (Ser139) Mouse Monoclonal Antibody |
| Açıklama | Mouse monoclonal Antibody |
| Konak | Mouse |
| Reaktivite | Human,Mouse |
| Konjugasyon | Unconjugated |
| Modifikasyon | Phosphorylated |
| İzotip | Mouse IgG1 |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Purified antibody in PBS with 0.05% sodium azide,0.5%protective protein and 50% glycerol. |
| Saflaştırma | Affinity Purification |
Antijen Bilgisi
| Gen Adı | Phospho-Histone H2A.X (Ser139) |
| Alternatif İsimler | H2A.X; H2AFX; H2a/x; HIST5-2AX; Histone H2A.X; gamma H2A.X |
| Gen Kimliği | 3014 |
| SwissProt Kimliği | P16104 |
| İmmünojen | Synthetic phosphopeptide corresponding to residues surrounding Ser139 of human H2A.X. |
Uygulama
| Uygulama | WB,ICC |
| Seyreltme Oranı | WB 1:500-1:1000,ICC 1:50-1:200 |
| Moleküler Ağırlık | Calculated MW: 15 kDa; Observed MW: 15 kDa |
Araştırma Alanı
Arka Plan
| Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. |
