PIM2 Rabbit Monoclonal Antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
Human,Mouse,Rat
Gen Adı
PIM2
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | PIM2 Rabbit Monoclonal Antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | Human,Mouse,Rat |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Purified antibody in PBS with 0.05% sodium azide,0.05% protective protein and 50% glycerol. |
| Saflaştırma | Affinity Purification |
Antijen Bilgisi
| Gen Adı | PIM2 |
| Alternatif İsimler | PIM2; Pim2h;;PIM2 |
| Gen Kimliği | - |
| SwissProt Kimliği | Q9P1W9 |
| İmmünojen | A synthesized peptide derived from human PIM2 |
Uygulama
| Uygulama | WB,ICC,IP |
| Seyreltme Oranı | WB 1:1000-1:2000,ICC 1:50-1:200,IP 1:20-1:50 |
| Moleküler Ağırlık | Calculated MW: 34 kDa ; Observed MW: 37 kDa |
Araştırma Alanı
Arka Plan
| Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression, the regulation of cap-dependent protein translation and through survival signaling by phosphorylation of a pro-apoptotic protein, BAD. Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase transcriptional activity. |
