PI3 Kinase p85 alpha Mouse Monoclonal Antibody-EnkiLife

PI3 Kinase p85 alpha Mouse Monoclonal Antibody

Konjugasyon: Unconjugated

Mouse monoclonal Antibody

Uygulama

IHC ICC/IF ELISA WB,IHC

Reaktivite

Human,Mouse,Rat

Gen Adı

PI3 Kinase p85 alpha

Saklama

Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.

Özet

Ürün Adı	PI3 Kinase p85 alpha Mouse Monoclonal Antibody
Açıklama	Mouse monoclonal Antibody
Konak	Mouse
Reaktivite	Human,Mouse,Rat
Konjugasyon	Unconjugated
Modifikasyon	Unmodified
İzotip	Mouse IgG1
Klonalite	Monoclonal
Form	Liquid
Konsantrasyon	Unconjugated
Saklama	Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Nakliye	Ice bags.
Tampon	Purified antibody in PBS with 0.05% sodium azide,0.5%protective protein and 50% glycerol.
Saflaştırma	Affinity Purification

Antijen Bilgisi

Gen Adı	PI3 Kinase p85 alpha
Alternatif İsimler	PIK3R1; GRB1; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alpha
Gen Kimliği	5295
SwissProt Kimliği	P27986
İmmünojen	Purified recombinant protein expressed in E.coli.

Uygulama

Uygulama	WB,IHC
Seyreltme Oranı	WB 1:500-1:1000,IHC 1:50-1:100
Moleküler Ağırlık	Calculated MW: 84 kDa; Observed MW: 84 kDa

Araştırma Alanı

TGF-beta signaling pathway,PI3K-Akt signaling pathway,Jak-STAT signaling pathway

Arka Plan

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.