NEFH Mouse Monoclonal Antibody
Konjugasyon: Unconjugated
Mouse monoclonal Antibody
Uygulama
Reaktivite
Human
Gen Adı
NEFH
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | NEFH Mouse Monoclonal Antibody |
| Açıklama | Mouse monoclonal Antibody |
| Konak | Mouse |
| Reaktivite | Human |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | Mouse IgG1 |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Purified antibody in PBS with 0.05% sodium azide |
| Saflaştırma | Affinity Purification |
Antijen Bilgisi
| Gen Adı | NEFH |
| Alternatif İsimler | NFH; CMT2CC |
| Gen Kimliği | 4744 |
| SwissProt Kimliği | P12036 |
| İmmünojen | Purified recombinant fragment of human NEFH (AA: 2-251) expressed in E. Coli. |
Uygulama
| Uygulama | IHC,ELISA |
| Seyreltme Oranı | IHC 1:200-1:1000,ELISA 1:5000-1:20000 |
| Moleküler Ağırlık | 112.4kDa |
Araştırma Alanı
Arka Plan
| Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. |