Lipocalin-2/NGAL Rabbit Monoclonal Antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
Mouse,Rat
Gen Adı
Lipocalin-2/NGAL
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | Lipocalin-2/NGAL Rabbit Monoclonal Antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | Mouse,Rat |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% protective protein. Stable for 12 months from date of receipt. |
| Saflaştırma | Affinity Purification |
Antijen Bilgisi
| Gen Adı | Lipocalin-2/NGAL |
| Alternatif İsimler | NRL; 24p3; Sip24; AW212229 |
| Gen Kimliği | 16819 |
| SwissProt Kimliği | P11672 |
| İmmünojen | Recombinant protein of mouse Lipocalin-2/NGAL |
Uygulama
| Uygulama | WB,IHC |
| Seyreltme Oranı | WB 1:500-1:2000,IHC 1:200-1:1000 |
| Moleküler Ağırlık | Calculated MW:23 kDa; Observed MW:23 kDa |
Araştırma Alanı
Arka Plan
| Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Iron-bound form (holo-24p3) is internalized following binding to the SLC22A17 (24p3R) receptor, leading to release of iron and subsequent increase of intracellular iron concentration. |
