KMT6 Rabbit Monoclonal Antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
Human,Mouse,Rat
Gen Adı
KMT6
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | KMT6 Rabbit Monoclonal Antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | Human,Mouse,Rat |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Purified antibody in TBS with 0.05% sodium azide,0.05%protective protein and 50% glycerol. |
| Saflaştırma | Affinity Purification |
Antijen Bilgisi
| Gen Adı | KMT6 |
| Alternatif İsimler | WVS; ENX1; KMT6; WVS2; ENX-1; EZH2b; KMT6A; EZH2 |
| Gen Kimliği | 2146 |
| SwissProt Kimliği | Q15910 |
| İmmünojen | A synthetic peptide of human KMT6/EZH2 |
Uygulama
| Uygulama | WB,ICC |
| Seyreltme Oranı | WB 1:500-1:1000,ICC 1:50-1:200 |
| Moleküler Ağırlık | Calculated MW: 85 kDa; Observed MW: 98 kDa |
Araştırma Alanı
Arka Plan
| Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Compared to EZH2-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. |
