HMG2 Mouse Monoclonal Antibody
Konjugasyon: Unconjugated
Mouse monoclonal Antibody
Uygulama
Reaktivite
Human
Gen Adı
HMG2
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | HMG2 Mouse Monoclonal Antibody |
| Açıklama | Mouse monoclonal Antibody |
| Konak | Mouse |
| Reaktivite | Human |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | Mouse IgG2b |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Purified antibody in PBS with 0.05% sodium azide. |
| Saflaştırma | Affinity Purification |
Antijen Bilgisi
| Gen Adı | HMG2 |
| Alternatif İsimler | High mobility group protein HMGI-C, High mobility group AT-hook protein 2, HMGA2, HMGIC |
| Gen Kimliği | 8091 |
| SwissProt Kimliği | P52926 |
| İmmünojen | This HMG2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from human HMG2. |
Uygulama
| Uygulama | WB |
| Seyreltme Oranı | WB 1:500-1:8000 |
| Moleküler Ağırlık | 11.8kDa |
Araştırma Alanı
Arka Plan
| This gene encodes a protein that belongs to thenon-histone chromosomal high mobility group (HMG) protein family.HMG proteins function as architectural factors and are essentialcomponents of the enhancesome. This protein contains structuralDNA-binding domains and may act as a transcriptional regulatingfactor. Identification of the deletion, amplification, andrearrangement of this gene that are associated with myxoidliposarcoma suggests a role in adipogenesis and mesenchymaldifferentiation. A gene knock out study of the mouse counterpartdemonstrated that this gene is involved in diet-induced obesity.Alternate transcriptional splice variants, encoding differentisoforms, have been characterized. |
