HDAC6 Mouse Monoclonal Antibody
Konjugasyon: Unconjugated
Mouse monoclonal Antibody
Uygulama
Reaktivite
Human
Gen Adı
HDAC6
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | HDAC6 Mouse Monoclonal Antibody |
| Açıklama | Mouse monoclonal Antibody |
| Konak | Mouse |
| Reaktivite | Human |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | Mouse IgG2b |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Purified antibody in PBS with 0.05% sodium azide |
| Saflaştırma | Affinity Purification |
Antijen Bilgisi
| Gen Adı | HDAC6 |
| Alternatif İsimler | HD6; JM21; CPBHM; PPP1R90 |
| Gen Kimliği | 10013 |
| SwissProt Kimliği | Q9UBN7 |
| İmmünojen | Purified recombinant fragment of human HDAC6 (AA: 482-800) expressed in E. Coli. |
Uygulama
| Uygulama | ELISA,FC |
| Seyreltme Oranı | ELISA 1:5000-1:20000,FC 1:200-1:400 |
| Moleküler Ağırlık | 131.4kDa |
Araştırma Alanı
| Autophagy |
Arka Plan
| Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. |
